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Sunday, Sept. 29 (Pre-conference Course)
Omics 101: A Primer for Clinical Practice
Phillips Hall, Siebens Building
Mayo Clinic in Rochester, Minn.Supported by the george m. eisenberg foundation for charities
This activity has been approved for AMA PRA Category 1 Credit(s)™.
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12:30 PM - 1:00 PM Fundamentals of Genetics and Genomics
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1:00 PM - 1:30 PM Genomic Testing: Laboratory Analysis of Genomic Information for Patient Care
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1:30 PM - 2:30 PM Genomic Testing: Data Analysis, Interpretation and Associated Challenges
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2:30 PM - 3:00 PM Break
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3:00 pm - 5:00 pm Implementation and Applications of Genomic Medicine in Practice -
- Roles and responsibilities of the health care team
- The diagnostic dilemma patient
- The cancer patient
- The drug-gene pair (pharmacogenomics)
- Question-and-answer session
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Monday, Sept. 30
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6:30 AM - 3:00 PM Registration
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7:00 AM - 8:00 AM Breakfast
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8:00 AM - 8:15 AM Welcome
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8:15 AM - 9:15 AM Plenary Session Eric D. Green, M.D., Ph.D., National Human Genome Research Institute
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9:15 AM - 10:15 AM Plenary Session Howard J. Jacob, Ph.D., Medical College of Wisconsin
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10:15 AM - 10:45 AM Break
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10:45 AM - 11:45 AM Plenary Session Wylie Burke, M.D., Ph.D., University of Washington
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11:45 AM - 1:00 PM Lunch
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1:00 PM - 2:30 PM Concurrent Session 1 The Diagnostic Dilemma -
Individualized medicine technologies offer new hope for patients for whom a diagnosis has been elusive. In this session, expert speakers will discuss how to best identify the patients most likely to benefit, counsel the patient and family, and filter genomic data to identify the genetic variants consistent with the patient's choices and present this in a meaningful report.
- Konstantinos N. Lazaridis, M.D., Mayo Clinic
- Kelly Ormond, M.S., C.G.C., Stanford University
- David L. Veenstra, Pharm.D., Ph.D., University of Washington
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1:00 PM - 2:30 PM Concurrent Session 2 The Lab -
How does the clinical laboratory develop new work flows and processes while meeting CLIA standards? How will the Food and Drug Administration apply method and result validation standards? How does one formulate the value equation needed to convince payers to reimburse for genomic testing?
- Heidi L. Rehm, Ph.D., Partners HealthCare Center for Personalized Genetic Medicine
- Elizabeth Mansfield, Ph.D., Food and Drug Administration
- Carl A. Gunter, Ph.D., University of Illinois at Urbana-Champaign
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1:00 PM - 2:30 PM Concurrent Session 3 Engaging in Education -
The practice of "genomic medicine" brings new information and paradigms of care into the clinical practice. Providers and patients are seeing new information and need to make decisions in a different way. Experts in this session will discuss approaches to physician and patient education.
- Katherine S. Hunt, M.S., C.G.C., Mayo Clinic
- Katherine Johansen Taber, Ph.D., American Medical Association
- Farris K. Timimi, M.D., Mayo Clinic
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2:30 PM - 2:45 PM Break
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2:45 PM - 3:30 PM Plenary Session Kelly Ormond, M.S., C.G.C., Stanford University
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3:30 PM - 4:30 PM Case study presentations
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Tuesday, Oct. 1
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6:30 AM - 3:00 PM Registration
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7:00 AM - 8:00 AM Breakfast
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8:00 AM - 8:15 AM Welcome
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8:15 AM - 9:15 AM Plenary Session Elaine R. Mardis, Ph.D., Washington University School of Medicine
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9:15 AM - 10:15 AM Plenary Session Mary V. Relling, Pharm.D., St. Jude Children's Research Hospital
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10:15 AM - 10:45 AM Break
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10:45 AM - 11:45 AM Plenary Session Gianrico Farrugia, M.D., Mayo Clinic
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11:45 AM - 1:00 PM Lunch
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1:00 PM - 2:30 PM Concurrent Session 1 Cancer Care -
What cancer patients are best suited for individualized medicine? How do we gain access to drugs when new and novel pathways are identified with the new technologies of individualized medicine? How do we overcome the bioinformatics and decision-support challenges presented by the complex nature of the cancer genome?
- Rafael Fonseca, M.D., Mayo Clinic
- Charles Erlichman, M.D., Mayo Clinic
- James Taylor, Ph.D., Emory University
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1:00 PM - 2:30 PM Concurrent Session 2 The Other "Omes" -
While most discussions about individualized medicine center on the genome, there are other "omes" that need to be considered. This session presents experts on mitochondrial DNA, the microbiome and the epigenome, and how we bring these into the clinical practice.
- Sihoun Hahn, M.D., Ph.D., University of Washington School of Medicine
- Joseph A. Murray, M.D., Mayo Clinic
- James G. Herman, M.D., Johns Hopkins Hospital
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1:00 PM - 2:30 PM Concurrent Session 3 Technology Trends -
The pace of technology innovations related to individualized medicine has been breathtaking. Hear the experts discuss how the various platforms compare, the new technologies coming, and how to interpret and manage the "big data" produced by these technologies.
- Matthew E. Hudson, Ph.D., University of Illinois at Urbana-Champaign
- Thom H. Dunning Jr., Ph.D., National Center for Supercomputing Applications
- J. Patrick Finn III, Ph.D., Fish & Richardson
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2:30 PM - 2:45 PM Break
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2:45 PM - 3:30 PM Plenary Session Raymond DuBois, M.D., Ph.D., Arizona State University
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3:30 PM - 4:30 PM Case study presentations
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4:45 PM - 6:30 PM Poster session and reception
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Wednesday, Oct. 2
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7:00 AM - 8:00 AM Breakfast
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8:00 AM - 8:05 AM Welcome
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8:05 AM - 9:05 AM Plenary Session Edward Abrahams, Ph.D., Personalized Medicine Coalition
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9:05 AM - 10:05 AM Plenary Session Dietrich A. Stephan, Ph.D., Silicon Valley Biosystems
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10:05 AM - 10:30 AM Break
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10:30 AM - 11:15 AM Plenary Session Joe Beery, Life Technologies
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11:15 AM - 12:00 PM Plenary Session Aleksandar Sekulic, M.D., Ph.D., Mayo Clinic
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12:00 PM - 12:15 PM Closing remarks
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